http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04342530-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557
filingDate 1991-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83aad4dbeb7f343be323b6e54aa49417
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publicationDate 1992-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H04342530-A
titleOfInvention 7-fluoroprostacyclin fatty emulsion
abstract PURPOSE: To provide the subject stable fatty emulsion containing a 7- fluoroprostacycline useful as a drug for circulatory organs, e.g. an antithrombotic drug as the active component. n CONSTITUTION: A fatty emulsion containing a chemically stable compound of the formula (R 1 is H or alkyl; R 2 is F; R 3 is 1-10C alkyl which may be substituted or cycloalkyl which may be substituted), e.g. 7-fluoro-1,6,17,18,19,20- pentanol-15-cyclopentylprostacycline as the active component. The above- mentioned fatty emulsion is mainly composed of a 7-fluoroprostacycline, 5-50W/V% soybean oil, preferably high-purity refined soybean oil, a phospholipid (e.g. yolk lecithin or soybean lecithin) in an amount of 1-50 pts.wt., preferably 5-30 pts.wt. based on 100 pts.wt. soybean oil and a proper amount of water and an auxiliary emulsifier, a stabilizer, an isotonicity forming agent, such as a polymer substance are added thereto as necessary. n COPYRIGHT: (C)1992,JPO&Japio
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Total number of triples: 25.