http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02292229-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75a4811e7eae15e0f1e32cc6a222ce30 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 |
filingDate | 1989-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcb1b64c7fd4ae35514fb8bbf1aeb586 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_818a63cac728833882d54c7ef65b1803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af78f0096c15db8a0c18c70695a387ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f22da65964b64ffb1d6ac69c5bfd0ff |
publicationDate | 1990-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H02292229-A |
titleOfInvention | Composition for long-acting preparation and its production |
abstract | PURPOSE: To obtain the subject composition consisting of crystalline and slightly soluble basic drug, higher fatty acid, enteric high polymer and surfactant, having no problem to stability of drug with a high reappearance and capable of providing uniformal effectiveness. n CONSTITUTION: The composition consisting of (A) crystalline and slightly soluble basic drug (e.g. nicardipine) or salt thereof, (B) higher fatty acid, preferably 12 to 18C higher fatty acid which is solid at ordinary temperature and 0.3 to 16 times by weight based on the ingredient A, (C) enteric high polymer, e.g. methacrylic acid-(meth)acrylic acid ester copolymer 0.3 to 16 times by weight based on the ingredient A and (D) surfactant, preferably nonionic surfactant 0.002 to 2 times by weight based on the ingredient A. Blend ratio of the ingredient A is 5 to 50wt.%, preferably 10 to 30wt.%. The abovementioned four ingredients are kneaded in prescribed weight ratio, pulverized and uniformed to prepare the abovementioned composition. n COPYRIGHT: (C)1990,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006511541-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003501375-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7211273-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005104914-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2000229886-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0178716-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005032588-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0781549-A2 |
priorityDate | 1989-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.