http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02193971-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_620ecb9324409347c27e96b6071503ee |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 |
| filingDate | 1989-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07b9b2078c36add656348d85cee15ae3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7eb2ac9c44254668d5d19dc6a9d45c97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cff5c671749f21bd4f1b94969305e2db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_635ed9fe5bc01b61742b8dc4d2048fd2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31849c89338912c3b96a5a990e3a6126 |
| publicationDate | 1990-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H02193971-A |
| titleOfInvention | Tri-substituted 2,3,4,5-tetrahydrobenzazepine derivative and intermediate thereof |
| abstract | NEW MATERIAL:Compounds of formula I [R 1 and R 2 are H, lower alkyl, lower alkoxycarbonyl lower alkyl or form 4-6 membered (lower alkyl substituted) heterocyclic group together with N; R 3 is H or lower alkyl; R 4 is (lower alkyl substituted)phenyl, naphthyl, etc.; n is 1-6] and salts thereof. n EXAMPLE: 7-Amino-3-[N-(2-naphthylsulfonyl)glycyl]-2-piperidinocarbonyl-2,3,4,5- tetrahydro-1H-3-benzazepine hydroiodate. n USE: A medicine free from severe side effects and used for prevention and remedy of thrombosis. n PREPARATION: A compound of formula II is reacted with a compound of formula III by a conventional amidation method to prepare a compound of formula IV (in case R 5 is CN) and the obtained compound is reacted with H 2 S, then a lower alkyl halide and subsequently ammonium acetate, etc., thus obtaining the objective compound of formula I. n COPYRIGHT: (C)1990,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009108032-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0675112-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5518982-A |
| priorityDate | 1989-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.