| abstract |
The present invention provides a novel compound that blocks hyperpolarization-activated cyclic nucleotide-dependent channels and is useful for heart failure, angina pectoris, myocardial infarction, hypertension, and the like, and a pharmaceutical composition containing the compound. A compound represented by the following formula (I) and a pharmaceutical composition containing the compound. Wherein R 1 is a hydrogen atom, R 2 to R 5 are a hydrogen atom, hydroxy, etc., R 6 to R 9 are a hydrogen atom, X is O, NH or CH 2 , m and p are , 0 or 1, n and q represent 1 or 2. ] [Selection figure] None |