| abstract |
NEW MATERIAL:A polypeptide in which plurality of amino acids are lost from N ends and/or C ends of human B cell stimulation factor 2 expressed by the formula, etc., and having antagonism action to the human B cell stimulation factor 2. n USE: A remedy and diagnostic for artrial myxoma, carcinoma of uterine cervix, endotoxin, shock, myeloma, chronic rheumatism, etc. n PREPARATION: For example, a method for successively bonding amino acids whose α-amino groups are protected according to normal Merrifield solid method by BOC method so as to synthesize a peptide chain is used and proceeding of coupling of the protected amino acid is carried out using Kaiser test while monitoring to provide the polypeptide in which plurality of amino acids are lost from N ends and/or C ends of human B cell stimulation factor 2. n COPYRIGHT: (C)1990,JPO&Japio |