| abstract |
PURPOSE: To obtain 5α-reductase inhibitor of high safety, which is useful as a remedy or prophylactic for a variety of diseases male hormone participates, using flavonoids as an active ingredient. n CONSTITUTION: Flavonoids of formulas I and II (R 1 is H, OH, gulculonic acid residue; R 2 R 4 WR 8 are H, OH; R 3 is N, OH, saccharide residue) such as kaempherol, quercetin or vicalin is used as an active ingredient, to produce pharmaceutical preparations such as tablets, powder, granules, capsules, solution, spray, injection, ointment or suppository. In case of oral administration, the dose is 20W200mg/adult/day in one to several portions. It is used for hair tonic, sebaceous gland inhibitor, alopecia, hirsutism, hidradenitis suppurativa, prostatic hypertrophy, and prostatic cancer. n COPYRIGHT: (C)1989,JPO&Japio |