abstract |
Strong 5α-reductase inhibitors are extracted andnfractionated from Thuja orientalisis and other similar crudendrugs or they may be purified as diterpenes in isolated form.nThe inhibitors are used either on their own or as activeningredients of therapeutics in the treatment of diseases causednby the overactivity of 5α-reductase or the hypersecretion ofnandrogens, such as male pattern baldness, androgeneticnalopecia, hirsutism, acne, prostatomegaly and cancer of thenprostate. |