| abstract |
PURPOSE: To obtain an optically protecting topical composition containing a specific chelating agent and useful for protecting the skin from a harmful effect caused by irradiation of ultraviolet rays such as sunburn, premature aging induced by the sunshine without preventing a sunburn response. n CONSTITUTION: This optically protecting topical composition containing chelating agent includes a safe and optically protective amount, preferably 1-10wt.% of the chelating agent having at least 50% inhibiting rate of hydroxy radical formation acting on the iron catalyst in an in vitro solution radical test or having at least 20% reducing rate of the skin wrinkle grade in an in vivo mouth skin wrinkle formation test, and safe and optically effective amount of topical carrier. The chelating agent is represented by an aromatic amine (e.g. 2,2'- dipyridylamine), an aromatic hydroxy acid (e.g. 2,3-dihydroxybenzoic acid), etc. The chelating agent is preferably applied to the skin in 0.001-1.0mg/cm 2 , preferably 0.01-0.1mg/cm 2 . n COPYRIGHT: (C)1989,JPO |