http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021527664-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
filingDate | 2018-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2021527664-A |
titleOfInvention | Synthetic peptide sp2 and its uses |
abstract | The amino acid sequence is SEQ ID No. The synthetic peptide sp2 which is No. 1 and its use are provided. As a medicinal feature, it has remarkable antitumor growth activity against heterologous transplanted tumors such as nude mouse subcutaneous human pancreatic cancer, human cervical cancer, and human ovarian cancer, and dose-effect relationship and time-effect relationship. Nude mouse orthotopic transplantation has the effect of delaying metastasis and prolonging survival for human pancreatic cancer and lung adenocarcinoma. As a safety feature, no toxic reactions or deaths have been seen since the animals were injected intravenously with a dose of 2000 mg / kg BW. Applications include (1) prevention and / or treatment of tumors, (2) suppression of tumor cell proliferation and / or growth, (3) enhancement of antitumor immune response, (4) induction of tumor cell differentiation, (5) class 1. Includes applications for the manufacture of antitumor agents, (6) suppression of tumor telomerase activity, (7) regulation of tumor cell cycle, (8) manufacture of products that control tumor cell cycle. [Selection diagram] None |
priorityDate | 2018-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.