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filingDate 2014-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01f235dab32c60a6b37bc164228f0430
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publicationDate 2014-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103819554-A
titleOfInvention Synthetic SP series polypeptides and application thereof
abstract The invention discloses synthetic SP series polypeptides and application thereof in treating cancer. The specific amino acid sequences of the synthetic SP series polypeptides are as shown in SEQ ID No. 1-11. The SP series polypeptides can be used for treating chronic myelogenous leukemia. The SP series polypeptides performs the function of treating leukemia by activating the activity of intracellular PP2A and conducting dephosphorylation on BCR/ABL, and also has a treatment effect on imatinib-resistant leukemia. The SP series polypeptides perform the function through SET/PP2A path, and have wide application in treating cancer.
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