abstract |
Provided herein are polymeric materials used, for example, in the delivery of short chain fatty acids. In particular, polymers are provided which form stable nanoscale structures and release their payloads, for example by covalent bond cleavage (eg by hydrolysis or enzymatic cleavage). The polymers are useful, for example, in the delivery of payloads (eg short chain fatty acids (SCFA)) to the intestine for therapeutic uses in health and disease, among others inflammatory, autoimmune, allergic, metabolic disorders. , And central nervous system diseases, and has wide applicability to diseases associated with changes in human microbiota. |