| abstract |
PROBLEM TO BE SOLVED: To provide a medicine or food or drink which has an osteoclast differentiation inhibitory action and an osteoblast differentiation promoting action and is useful for the regulation of bone and tooth metabolism. SOLUTION: Osteoclast differentiation inhibitor, osteoblast differentiation promoter, bone resorption inhibitor, bone formation promoter, bone metabolism regulator, bone-reducing disease containing an lignan compound derived from a pepper family plant as an active ingredient. Prophylactic and / or therapeutic agent. [Selection diagram] None |