http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019144097-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60e66be87630d7cef0ce770e1d898eec |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
| filingDate | 2018-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4e8d4001c86becbd2efcecd45e395bd |
| publicationDate | 2019-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2019144097-A |
| titleOfInvention | Method for detecting abnormal condensation of chromatin |
| abstract | [PROBLEMS] To identify phosphorylated peptides necessary for chromosome condensation by utilizing early chromosome condensation that can induce only chromatin condensation from interphase cells, which is an approach different from conventional methods, and to phosphorylate the peptide. To provide a method for detecting abnormal condensation of chromatin by using the degree as an index. SOLUTION: (1) AHCTF1, ATRX, BAZ1A, BAZ1B, CBX8, CDCA8, CHAF1A, CTDSPL2, CSNK2B, DNTTIP2, in a cell population to be detected including cells in cell division or cells in which early chromosome condensation has been induced. DSG2, ELAVL1, GTF21, HDGF, Histone H4, H2AFY, HMGA1, HP1BP3, ILF3, KIF22, KIF4A, LIG3, LMNA, MKI67, MBD1, MLL, MTA1, MYBBP1A, NONO, NUMA1, NUP107, PARP1, PSIP1, PLIP1, PSIP1, PSIP1 The degree of phosphorylation of one or more proteins selected from the group consisting of RRP1B, SAFB2, SGOL1, TCF20, TERF2, TFPT, TMPO α, TMPO β / γ, TUBA1B, UTP14A, VIM, ZC3HAV1, ZNF280C and ZNF512B And (2) abnormally condensed chromatin is detected when the degree of phosphorylation of the protein in the cell population to be detected is low compared to the degree of phosphorylation of the protein in the control cell population. Abnormal condensation of chromatin, including the process of evaluating Detection method. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220160611-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021200545-A1 |
| priorityDate | 2018-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 393.