abstract |
An adeno-associated virus (AAV) serotype AAV-Rh74 and related AAV vectors, and AAV-Rh74 and related AAV vectors provide gene transfer methods and methods of use. SOLUTION: The AV capsid sequence is an amino acid substitution of any one of amino acid positions 195, 199, 201, or 202 of RH74 VP1 capsid sequence, or lysine in RH74 VP1 capsid sequence. AAV capsid sequence with amino acid substitution for arginine. 【Selection chart】 None |