abstract |
The present invention provides a series of compounds that modulate the function of nuclear hormone receptors, in particular androgen receptors. Kind Code: A1 The present invention relates to compounds of hydantoins and methods of using such compounds in the treatment of age related diseases such as androgen receptor related pathologies such as prostate cancer, and pharmaceutical compositions containing such compounds. Related to things. In one embodiment, the pharmaceutical composition comprises a therapeutically effective amount of a compound according to Formula II, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, diluent or adjuvant. The present invention provides a series of compounds that modulate the function of the nuclear hormone receptor, in particular the androgen receptor. These compounds can cause the disappearance of prostate cancer cells and tumors. 【Selection chart】 None |