| abstract |
The present invention provides an anti-androgen compound having good affinity for an androgen receptor while lacking androgenic activity. A compound having the following structure or a salt thereof: (Wherein n is 0 to 6; m is 0 to 1; J and Y are direct bonds or bonds such as —O—, —CO—, —CH 2 —, etc .; Ra and Rb, R 1 is H, halogen R 2 is H, halogen, CF 3 etc .; R 3 is halogen, CN, NO 2 etc .; R 4 and R 5 are H, halogen, alkyl etc., or R 4 and R 5 are orthophenylene rings. Formation; R 6 and R 7 are alkyl or the like, or R 6 and R 7 form a ring having (CH 2) p (p is 2 to 6); W is O and S; G 1 to G 10 are C, CH, N, NO, etc .; Y is linked to G 1 , G 2 or G 4 ) [Selection figure] None |