| abstract |
The present invention provides an antibody against hepatitis B surface antigen (HBsAg) (particularly a humanized antibody), a nucleic acid molecule encoding the same, a method for preparing the same, and a pharmaceutical composition containing the same. The invention also provides the use of antibodies and pharmaceutical compositions. The antibody and pharmaceutical composition according to the present invention neutralize HBV pathogenicity in a subject (eg, human) in order to prevent and / or treat HBV infection or a disease associated with HBBV infection (eg, hepatitis B). Or can be used to reduce HBV DNA and / or HBsAg serum levels in a subject. |