abstract |
The present invention relates to a compound of formula (I): [wherein all variables are as defined in the description], or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof. Provide salt. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. The invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and / or inflammatory disorders using them. |