abstract |
The present invention relates to a compound of formula (I): (Wherein all variables are as defined herein), or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate thereof. These compounds are selective factor XIa inhibitors or dual inhibitors of factor XIa and plasma kallikrein. The present invention also relates to pharmaceutical compositions comprising these compounds and methods for treating thromboembolic and / or inflammatory diseases using these compounds. |