| abstract |
Useful for the treatment or prevention of disorders associated with neuropathic pain, inflammatory pain, conditions associated with irritability, decreased nerve conduction velocity, cell proliferation disorders, imbalance between bone resorption and bone formation Provision of compounds. A compound comprising a piperazine system in which a specific 2-position that antagonizes an angiotensin type II2 (AT2) receptor is substituted with a carboxyl group or a derivative thereof. It also relates to compositions containing the compounds and their use in methods of treating or preventing the disorder or disease. [Selection figure] None |