abstract |
A novel boron-containing compound useful for boron neutron capture therapy (BNCT) in cancer treatment is provided. A compound represented by the following formula: (Black circles represent B atoms, white circles represent B—H; —R 1 represents — (CH 2 ) n —X 1 —R 3 (n represents an integer of 0-6; X 1 represents Represents, or is absent, O, S, NH, S—S, O—CO, NHCO, or SCO; R 3 is C 6 -C 20 alkyl, hydroxy C 6 -C 20 alkyl, amino C 6- C 20 alkyl, azide C 6 -C 20 alkyl, hydroxycarbonyl C 6 -C 20 alkyl, etc.) or — (CH 2 ) 2 —O— having a repeating sequence of 3 to 10 times and oxygen Represents a group having a methyl group or an ethyl group at the end of the atom side). [Selection figure] None |