abstract |
A new class of boron showing a desirable profile of cell selectivity, in vivo stability and ability to easily cross cell membranes for use in boron neutron capture therapy (BNCT) and antisense oligonucleotide method (AOT) Provision of containing nucleosides and oligonucleotides. Oligonucleotides comprising at least one uncharged 3 ', 5'-O, O-[(carborane-1-yl-methyl) phosphonate] internucleotide linkage. [Selection] Figure 1 |