| abstract |
The present invention provides a series of compounds that modulate the function of nuclear hormone receptors, particularly androgen receptors. The present invention relates to compounds of hydantoins and methods of using such compounds for the treatment of age-related diseases such as androgen receptor related pathologies such as prostate cancer, and pharmaceutical compositions containing such compounds. Related to things. In one embodiment, the pharmaceutical composition comprises a therapeutically effective amount of a compound according to Formula II, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, diluent or adjuvant. The present invention provides a series of compounds that modulate the function of nuclear hormone receptors, particularly androgen receptors. These compounds can cause the disappearance of prostate cancer cells and tumors. [Selection figure] None |