abstract |
The present invention provides a novel method for synthesizing maxacalcitol and intermediates. In the method of the present invention, vitamin D2 is used as a starting material, a compound represented by formula II is obtained, oxidized, asymmetrically reduced, a side chain is added, a hydroxyl group is introduced at the C-1 position, photochemistry Maxacalcitol is creatively synthesized through steps such as inversion. |