| abstract |
The present invention discloses quinine compounds, pharmaceutically acceptable salts, solvates, precursors and optical isomers thereof. The present invention further provides that the above compound selectively blocks M 1 and M 3 receptor subtypes, and the action on M 2 receptor is not remarkable, and rhinitis, cold rhinitis, chronic tracheitis, airway hyperresponsiveness, asthma Treating chronic obstructive pulmonary disease, cough, urinary incontinence, frequent urination, overactive bladder syndrome, bladder spasm, cystitis, and gastrointestinal diseases such as irritable bowel syndrome, convulsive colitis, duodenal ulcer, gastric ulcer, etc. In some cases, it is disclosed that it has the characteristics that it is fast-acting, has long medicinal properties, and has little toxicity and side effects. [Selection figure] None |