http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004517123-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-02 |
| filingDate | 2001-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2004517123-A |
| titleOfInvention | Novel quinuclidine derivative and pharmaceutical composition containing the same |
| abstract | A compound of formula (I), wherein B is a phenyl ring, a 5- to 10-membered heteroaromatic group containing one or more heteroatoms, or naphthalenyl, 5,6,7,8-tetrahydronaphthalenyl , Benzo [1,3] dioxolyl or biphenyl group; R 1 , R 2 and R 3 each independently represents a hydrogen atom or a halogen atom, or a hydroxy group, a phenyl group, —OR 7 , —SR 7 , —NR 7 R 8 , —NHCOR 7 , —CONR 7 R 8 , —CN, —NO 2 , —COOR 7 or —CF 3 group, or a linear or branched, substituted or unsubstituted lower alkyl group Wherein R 7 and R 8 each independently represent a hydrogen atom, a linear or branched lower alkyl group, or together form an alicyclic ring; or R 1 and And R 2 together form an aromatic or alicyclic or heterocyclic ring. n is an integer of 0 to 4; A is —CH 2 —, —CH═CR 9 —, —CR 9 ═CH—, —CR 9 R 10 —, —CO—, —O—, —S—, A group selected from —S (O) —, —S (O) 2 — and —NR 9 , wherein R 9 and R 10 are each independently a hydrogen atom, linear or branched; Represents a lower alkyl group or together forms an alicyclic ring; m is an integer from 0 to 8, provided that when m = 0, A is not —CH 2 —; And the substitution of the azoniabicyclo ring can be in the 2, 3, or 4 position, including all possible configurations of the asymmetric carbon atom; R 4 represents a group of the structure: (formula II), wherein R 11 is a hydrogen or halogen atom, a hydroxy group, an alkoxy group, a nitro group, a cyano group, —CO 2 R 12 or —NR 12 R 13 [here Wherein R 12 and R 13 are the same or different and are selected from hydrogen and a linear or branched lower alkyl group], or a linear or branched, substituted or unsubstituted lower alkyl group R 5 represents an alkyl group of 1 to 7 carbon atoms, an alkenyl group containing 2 to 7 carbon atoms, or a group of formula (III), where q = 1 or 2, and R 11 is as defined above; R 6 represents a hydrogen atom, a hydroxy group, a methyl group or a —CH 2 OH group; and X − represents a pharmaceutically acceptable anion of a monovalent or polyvalent acid. Represent. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016528199-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010519193-A |
| priorityDate | 2000-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 368.