abstract |
Formula (II): A compound of the formula (wherein A, R 1 , R 2 , R 5 , and R 13 are described herein) or a stereoisomer, enantiomer, or tautomer, or mixture thereof; Or a pharmaceutically acceptable salt or solvate thereof is described herein, and other compounds are also described herein. These compounds have activity as SHIP1 modulators and may therefore be useful in the treatment of various diseases, disorders, or conditions that would benefit from SHIP1 modulation. Compositions comprising the compounds of the invention are also disclosed, and methods for modulating SHIP1 by administration to animals in need of such compounds are also disclosed. |