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filingDate 2014-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2016511828-A
titleOfInvention Analyte extraction apparatus and method
abstract In a complex sample matrix, the concentration of a glycopeptide antibiotic containing a phenolic moiety such as vancomycin is determined from the complex part of the sample matrix to the extractant with affinity for the glycopeptide antibiotic. And extracting the glycopeptide antibiotic by exposing the extractant to a metered portion of the eluate to release the glycopeptide antibiotic from the extractant; and Gibbs reagent (2,6-dichloroquinone-4 Activation in the eluate after the Gibbs reagent is activated and the reaction between the activated Gibbs reagent and the antibiotic is stabilized Detects reaction products between Gibbs reagent and antibiotics and detects complex reaction product in complex sample matrix Identifying a concentration of glycopeptide antibiotics by identifying the concentration of the raw material, method and apparatus for performing the is disclosed. Also disclosed is a method of designing an individualized drug dosing regimen using the concentrations thus obtained.
priorityDate 2013-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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