abstract |
Disclosed are an inhibitor of poly (ADP-ribose) polymerase (PARP), a method for producing the inhibitor, and a method for treating a patient using the inhibitor. A compound exemplified by formula (IV). (One of R1A and R1B is H and the other is R1, OR1, SR1, S (O) R1, SO2R1, NH2, NHR1, N (R1) 2, C (O) R1, C (O) NH2, C ( O) NHR1, C (O) N (R1) 2, NHC (O) R1, NR1C (O) R1, NHSO2R1, NR1SO2R1, NHC (O) OR1, NR1C (O) OR1, SO2NH2, SO2NHR1, SO2N (R1) 2, NHC (O) NH2, NHC (O) NHR1, NHC (O) N (R1) 2, OH, C (O) OH, CN, CF3, OCF3, CF2CF3 or halogen) [Selection] None |