http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015535304-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2560-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-143333 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 |
filingDate | 2013-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2015535304-A |
titleOfInvention | Microfluidic chip for solid-phase glycan and glycopeptide analysis, and glycomic extraction, analysis and methods for using the same |
abstract | New highly specific solid phase methods for analyzing glycans and proteoglycans using solid phase systems are provided. The present invention also provides an integrated device and method of use, including high-throughput glycan isolation and reverse phase liquid chromatography (RPLC) for on-chip glycan extraction, modification and separation. The N-glycan coverage detected by the GIG-chip-LC device of the present invention can be significantly improved, especially for low abundance species. Chip-LC with PGC minimizes the dynamic range of glycan concentration in the fraction and results in the detection of low abundance glycans. Glycan isomers can be separated by the tip-LC portion of the device. The GIG-chip-LC device of the present invention can be used to analyze glycans derived from tissue and serum samples, thus providing a reliable tool for glycomic analysis. The reproducible ability and ability to detect unique glycans derived from tissue samples provides a powerful means for finding abnormal glycans associated with disease states. [Selection] Figure 1 |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10877043-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022149560-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102091636-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102100158-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020153502-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200027064-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200028917-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018109525-A |
priorityDate | 2012-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 288.