| abstract |
Acting as an immunosuppressant for organ transplantation and as a prophylactic and therapeutic agent for immune reactions caused by autoimmune diseases, diseases with hyperfunctional inflammatory responses, allergies, cancer, and some other therapeutic agents Providing new or improved agents that inhibit kinases, eg, Janus kinases. The present invention modulates the activity of Janus kinase and is useful in the treatment of diseases associated with the activity of Janus kinase, such as immune related diseases, skin disorders, myeloproliferative disorders, cancer, and other diseases. Heteroaryl substituted pyrrolo [2,3-b] pyridine (I) and heteroaryl substituted pyrrolo [2,3-b] pyrimidines are provided. [Selection figure] None |