abstract |
A polymeric composition useful for coating implantable devices such as drug eluting stents. The polymer main chain comprises polylactide (PLA), poly (L-lactide) (PLLA), poly (D, L-lactide-co-glycolide) (PLGA), poly (e-caprolactone) (PCL), Poly (ester amide) (PEA), polycarbonate, parylene, polytetrafluoroethylene (PTFE), polyurethane (PU), polyurethane urea (PUU) and combinations thereof, wherein the first end is capped by a phosphorylcholine moiety, A hydrophobic polymer having a biodegradable or non-degradable polymer backbone capped with a functional moiety F at two ends, an amphiphilic polymer or amphiphilic di- or triblock polymer, a hydrophilic biopolymer, The hydrophobic polymer includes a chemical moiety R to which F binds or reacts. . [Selection figure] None |