| abstract |
The present invention provides non-particulate crosslinked poly-ε-lysine polymers. The poly-ε-lysine and the crosslinker are linked by an amide bond, and the crosslinker has at least two functional groups that can react with the alpha carbon amine of the poly-ε-lysine. The polymer is suitably insoluble in water and other solvents and is provided in a macro form such as, for example, a sheet, article, or fiber. Macro-shaped polymers are used in a wide variety of applications, such as wound healing, medical supports including particulate supports and functional materials attached or retained to the supports, as well as peptides, oligonucleotides, Useful in solid-phase synthesis of oligosaccharides, species immobilization, cell culture, and chromatographic separation. |