| abstract |
8-PN and suitable to distribute the drug continuously during the gastrointestinal transit time, which is generally 12-16 hours, and to be administered preferably once a day, preferably before going to bed An oral formulation containing a progestin, preferably DRSP, is provided. The present invention relates to an oral modified release formulation in combination with a phytoestrogen, 8-prenylnaringenin (8-PN), and a progestin, preferably drospirenone, and some uses thereof. According to another aspect of the present invention, an oral modified release formulation of 8-prenylnaringenin and an immediate release progestin, such as drospirenone, is provided with some of its use. [Selection figure] None |