| abstract |
Disclosed is a pharmaceutical dosage unit for use in hormone replacement therapy, comprising drospirenone and an estrogen sulfamate, such as estradiol sulfamate or estriol sulfamate. The combination therapy can comprise continuous or discontinuous administration of drosprenone and / or estrogen sulfamate, for example, weekly administration of both agents, or weekly administration of estrogen sulfamate and daily administration of drospirenone. . |