| abstract |
A method of preparing and resulting product comprising a substrate having a surface, a bulk under the surface, and a graft polymer layer on the substrate surface, wherein the substrate surface and the graft polymer layer are combined in a fibrinogen binding assay. Constructing a modified surface having a fibrinogen adsorption of less than about 125 ng / cm 2 , in this fibrinogen binding assay, the modified surface is 70 μg containing 1.4 μg / mL I-125 radiolabeled fibrinogen at 37 ° C. for 60 minutes. The method is incubated in fibrinogen from / ml human plasma. |