abstract |
Disclosed is a solid buccal pharmaceutical composition containing agomelatine intended for systemic action. Agomelatine, or hydrates, complexes, co-crystals, crystalline forms thereof, one of addition salts with pharmaceutically acceptable acids or bases, and diluents, binders, flow agents, lubricants A solid buccal pharmaceutical composition intended for systemic action, comprising one or more excipients selected from agents, coating agents, plasticizers, flavoring agents, counter-irritants and sweeteners, A composition characterized in that it makes it possible to obtain an absolute bioavailability of more than 25%. [Selection figure] None |