abstract |
The present invention is caused and mediated by piperidine and pyrazine derivatives according to formulas (Ia), (Ib) and (II) as autotaxin inhibitors, and increased lysophosphatidic acid levels and / or activation of autotaxin, It relates to the use of such compounds for the treatment and / or prevention of and / or amplified physiological and / or pathophysiological conditions, in particular various cancers. |