| abstract |
(57) Abstract: The present invention provides a compound of the general formula (I) wherein A 2 , A 4 , A 6 and A 8 have beneficial pharmacological properties, in particular, an inhibitory effect on signal transduction caused by tyrosine kinase. [5,4-d] pyrimidines, their tautomers, stereoisomers and salts with inorganic or organic acids or bases, in particular their physiology The present invention relates to the above acceptable salts, their use in treating diseases, especially tumors, as well as their production. |