| abstract |
The present invention relates to compounds defined by formula (I) having the useful pharmacological activity, wherein the groups R 1 and R 2 are as defined in claim 1. In particular, the compounds are inhibitors of 11β-hydroxysteroid dehydrogenase (HSD) 1 and are therefore affected by inhibition of this enzyme such as metabolic diseases, particularly type 2 diabetes, obesity, and dyslipidemia. Suitable for the treatment and prevention of possible diseases. |