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filingDate 2011-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2012-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2012072133-A
titleOfInvention Small sustained release formulation of ambroxol hydrochloride
abstract [PROBLEMS] To provide a miniaturized preparation of ambroxol hydrochloride that is easy to drink for children and elderly people with reduced swallowing function and that is guaranteed effective and safe as a once-daily sustained release preparation. provide. A granule having a layered structure of at least three layers, comprising a core particle, a first layer containing ambroxol hydrochloride covering the core particle, a disintegrant and a binder, a water-insoluble polymer and a water-soluble polymer A granule comprising a second layer comprising molecules and a third layer comprising ambroxol hydrochloride and a binder. [Selection figure] None
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