abstract |
The present invention describes non-steroidal compounds of general formula (I) as estrogens: wherein A is formula (II), wherein X 1 is one or more groups on the phenyl ring and each other independently, halogen, OH, (C 1 -C 4) alkyl, (C 1 -C 4) alkyl -O, (C 3 -C 6) cycloalkyl -O, (C 1 -C 14) acyl -O , (C 1 -C 4 ) alkenyl, (C 1 -C 4 ) alkynyl, perfluoro (C 1 -C 4 ) alkyl, -CHO or CN group, and X 2 is one or more on the phenyl ring And independently of each other, H, halogen, OH, (C 1 -C 4 ) alkyl, (C 1 -C 4 ) alkyl-O, (C 1 -C 4 ) alkenyl, (C 1 -C 4 ) Alkynyl, perfluoro (C 1 -C 4 ) alkyl, —CHO or CN group. |