http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010538063-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-026 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-10 |
| filingDate | 2008-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2010538063-A |
| titleOfInvention | Methods and intermediates for chemical synthesis of polypeptides and proteins |
| abstract | The present invention provides methods and intermediates for chemical synthesis of polypeptides and proteins, more particularly peptide fragments containing N-terminal β (beta) -methyl-cysteine (SEQ ID NO: 1) having a C-terminal thioester. It relates to methods and intermediates for producing β (beta) -amino-thioester intermediates that are chemically linked to another peptide fragment and spontaneously rearrange to form an amide bond. The present invention also includes a method for synthesizing β (beta) -methyl-cysteine (SEQ ID NO: 1) and its protected forms. Moreover, the present invention relates to converting β (beta) -methyl-thiazolidine residues of polypeptides and proteins to β (beta) -methyl-cysteine (SEQ ID NO: 1) residues. [Selection] Figure 1 |
| priorityDate | 2007-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.