abstract |
The present invention relates to phenylpropionamide compounds of formula (I) and pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein A, B, R 1 , R 2 , R 3 , R 4 , And R 5 are defined as described herein. The present invention is also directed to the use of a compound of formula (I) for treating, preventing or alleviating a disorder responsive to activation of opioid receptors, particularly μ-opioid receptors. The compounds of the present invention are particularly useful for the treatment of pain. |