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filingDate 2007-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2010-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2010508053-A
titleOfInvention Swallowable multi-nozzle dosing device for releasing drugs in the digestive tract
abstract Disclosed are capsules and methodologies for administering a drug in the gastrointestinal tract of a mammal. The gastrointestinal tract has a tissue site of interest. The capsule has a drug reservoir; a plurality of drug dispensing means such as a plurality of piezoelectric droplet jet nozzle dispensers; a power source; and the amount and time duration of drug administration into the gastrointestinal tract by the drug dispensing means Electronic control circuit means and / or detection means capable of communicating with the drug application means; for example, the drug reservoir, the drug application means and the non-digestible outer protective shell housing the electronic control circuit means May be. A plurality of the nozzle dispensers of the drug application means are disposed relative to the surface of the housing such that the capsule is rotated and / or translated during drug release to uniformly release the drug to a tissue site of interest. Is located tangentially. Furthermore, drug release by the intestine in the gastrointestinal tract is facilitated by using a plurality of nozzles and releasing the drug at high speed.
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