| abstract |
A novel opener of a novel PTEN inhibitor or a large conducting Ca 2+ activated K + channel (Maxi-K channel), the survival of normal cells, brain cells, heart cells, and skin. And a therapeutic agent that is useful as a drug that inhibits gram-negative sepsis and cell migration and cell invasion by inhibiting PTEN, and is further useful in the treatment of nervous system disorders. Formula (I): A tetrazolylalkoxydihydrocarbostyryl compound wherein R is cycloalkyl, A is lower alkylene, and the bond between the 3 and 4 positions of the carbostyryl ring is a single or double bond; Or a salt thereof and a therapeutic agent comprising the compound as an active ingredient. [Selection figure] None |