| abstract |
Novel pyrrolidine-based and thiazolidine-based inhibitors of dipeptidyl peptidase IV (DPP-IV) and diabetes, particularly type 2 diabetes, as well as impaired glucose tolerance, glucose homeostasis, and complications associated with diabetes Providing a method for treating Pyrrolidine and thiazolidine DPP-IV inhibitory compounds. Also, a synthetic method for producing the above compound and its related compounds, a DPP-IV inhibition method using the above compound, and a pharmaceutical preparation for treating DPP-IV mediated diseases, particularly type 2 diabetes, containing them. [Selection figure] None |