abstract |
The present invention provides a novel 5-membered heterocyclic compound useful for the treatment and / or prevention of diabetes and related diseases. SOLUTION: General formula (1) Compounds and their salts; processes for the preparation of these compounds; their therapeutic and cosmetic applications in the treatment of aging-related and diabetic vascular complications; AGE disruptors, AGE inhibitors and radical scavengers; Pharmaceutical and cosmetic compositions comprising these compounds; and methods for the treatment of diseases caused by AGE and / or radical deposition in somatic cells. [Selection figure] None |