| abstract |
Disclosed is a method for eliminating or preventing vasoconstriction and preventing or reducing blood flow in a pedicle flap or other microsurgery. A method of preventing necrosis in a pedicled flap or in any microvascular surgery, the method comprising a therapeutically effective amount of a vasodilator composition on a stem or other blood source. Wherein the composition contains NO or a NO donor or a prodrug that causes formation of nitrosothiol in the tissue, optionally in combination with lidocaine. [Selection figure] None |