| abstract |
Compounds of formula (I) and their stereoisomers, geometric isomers, tautomers, solvates, metabolites, salts, and pharmaceutically acceptable prodrugs, inhibit receptor tyrosine kinases, and It is useful for the treatment of hyperproliferative disorders mediated thereby. For in vitro, in situ, and in vivo diagnosis, prevention, or treatment of such disorders of mammalian cells, or related pathological conditions, compounds of formula (I) and stereoisomers, geometric isomers thereof , Tautomers, solvates, and methods of using pharmaceutically acceptable salts are disclosed. |